Team size
1-10
Location
Milan, Italy
Foundation date
2022
Funding stage
Unknown
Amount raised
Unknown
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Reprogramming DNA methylation by RNA therapeutics to cure intractable conditions
We discovered a new class of specialized RNAs interacting with the mammalian DNMT1 – DNMT1-interacting RNAs (DiRs). DiRs prevent DNA methylation and gene silencing in a locus-specific manner, by binding and inhibiting DNMT1 are able to reactivate suppressed genes